International Journal of Recent Innovations in Medicine and Clinical Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN:-
Online ISSN:-2582-1075
Original Article
Author Details :
Volume : 2, Issue : 2, Year : 2020
Article Page : 19-23
https://doi.org/10.18231/j.ijrimcr.2024.004
Abstract
Introduction: Hematological abnormalities are common in people with HIV infection. These abnormalities may be due to HIV infection itself, opportunistic infections, HIV-related malignancies, or secondary to the treatments used in HIV infection.
Material and method: We report a retrospective study spread over a period of 3 years, relating to patients whose haematological assessment was sent to the laboratory of the Avicenne military hospital in Marrakech. We included in this study, all HIV-positive patients. Excluded were HIV-positive patients for whom the myelogram was not requested. Results: 20 HIV positive patients whose myelogram was sent to the hematology laboratory. The average age was 37.46 years. The sex ratio was 0.5. Anemia was observed in 80% of patients. The most predominant type of anemia was normochromic normocytic anemia, found in 42% of cases. The total number of leukocytes ranged from 1,500 to 19,000 cells / mm3. The number of platelets varied from 20,000 to 500,000 / mm3. The blood smear was performed in all of our patients and who showed globular abnormalities. 2 smears had revealed the presence of lymphoblasts. The myelogram showed images of activated macrophages without hemophagocytosis in 25% of the cases, a macrophagic activation syndrome in 20% of the patients and an acute lymphoblastic leukemia type Burkitt in 10% of the marrow. The bone marrow was mostly reactive (45%). Conclusion: Haematological manifestations are frequent in patients infected with HIV. These abnormalities must be managed to reduce the patient's morbidity.
Keywords: HIV, hematological abnormalities, anemias, bone marrow.
How to cite : Khayati* S, Bahri R, Ferssani F E, Yahyaoui H, Ameur M A, Chakour M, Biological Haematological Manifestations of HIV Infection. Int J Recent Innov Med Clin Res 2020;2(2):19-23
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