Print ISSN:-
Online ISSN:-2582-1075
Original Article
Author Details :
Volume : 2, Issue : 3, Year : 2020
Article Page : 101-105
https://doi.org/10.18231/j.ijrimcr.2024.027
Abstract
Background: Diabetes mellitus is the most common metabolic disorder characterized by metabolic abnormalities and long term complications. The presence of high levels of plasma fibrinogen is predictive of vascular complications and cardiovascular death in patients with diabetes mellitus. The increased prevalence of Coronary Artery Disease (CAD) in diabetic patients makes it important to evaluate changes in plasma fibrinogen. Aim and Objectives: The present study was undertaken to estimate plasma fibrinogen level in patients with diabetes type II and its correlation with glycemic control. Methods and materials: The study was conducted in Al Wahda hospital, and from different clinic in Derna city. The study included 53 patients with diabetic mellitus type II and 19 non diabetics (as control) without coronary artery disease (CAD). Plasma fibrinogen level was estimated in all cases and controls, and it’s correlated with glycemic control in diabetic. Results: Mean plasma fibrinogen level in patients with diabetic mellitus type II was high (447±22.2mg/dl) as compared to controls (198±0.82 mg/dl), which was found to be statistically highly significant (p=0.001). Our study showed fibrinogen to be significantly associated with the glycocylated hemoglobin (HbA1c) Fibrinogen level increased as the value of HbA1c became higher (459±22.8 mg/ dl ) when HBA1C ? 7%. Conclusion: Patients with type 2 diabetes mellitus had a higher plasma fibrinogen level. Fibrinogen level was significantly correlated with glycemic control. Keywords: Fibrinogen, Diabetes mellitus, HbA1c, Derna, Libya.
How to cite : Elhassade A, Saad A, Falleh A, Alamin K, Eltira E, Fibrinogen Level in Non-Insulin Dependent Diabetes Mellitus (NIDDM). Int J Recent Innov Med Clin Res 2020;2(3):101-105
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