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Ampicillin Resistance Pattern and Aerobic Bacterial Profile in Diabetic Foot Infection Patients in Bangladesh

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Original Article

Author Details : Mohammad Asaduzzaman**, Tafriha E Tasdika , Fabiha Tasnim Aroni , Sumi Rani Dey , Md. Rezaul Islam , Shamima Akter

Volume : 4, Issue : 4, Year : 2022

Article Page : 25-33

https://doi.org/10.18231/j.ijrimcr.2022.029

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Abstract

Introduction: The goal of this study was to determine the frequency of bacterial isolates cultured from diabetic foot infections and to assess their Ampicillin resistance and susceptibility.

Methods: A total of 377 diabetic foot lesions were included in this prospective analysis. The antibiotic susceptibility pattern of bacteria isolated from foot lesions was assessed using the Kirby-Bauer disk diffusion method.

Results: The most commonly isolated Gram-positive bacteria were Staphylococcus aureus, followed by Enterococcus spp. and CoNS. The most commonly isolated Gram-negative bacteria were Klebsiella spp., Pseudomonas spp., Proteus spp., Escherichia coli, Enterobacter spp., Citrobacter spp., Citrobacter freundii, and Proteus vulgaris. Ampicillin was found to be 100.0% resistant against Citrobacter spp., and Serratia mercescens but their numbers are few. Pseudomonas spp. was found 93.2% resistant and followed by Klebsiella spp. (91.7%), CoNS spp. (90.0%), Staphylococcus aureus (86.1%), Acinetobacter spp. (81.8%), Proteus spp. (81.0%), Escherichia coli (74.1%), Enterobacter spp. (70.0%), Proteus vulgaris (66.7%), Staphylococcus aureus (84.30%), Pseudomonas aeruginosa and Citrobacter freundii were both found 50.0% resistant.

Conclusion: The present study confirmed the prevalence of ampicillin drug-resistant pathogens (83.3%) in diabetic foot ulcers. The diverse bacteria infecting the wound must be evaluated, as well as the antibiotic susceptibility patterns of the isolates from the infected lesion. This information is critical for selecting the right medications, eliminating resistance trends, and lowering healthcare costs.

Keywords: Diabetic Foot Infection, Polymicrobial Infections, Ampicillin.

How to cite : Asaduzzaman* M, Tasdika T E, Aroni F T, Dey S R, Islam M R, Akter S, Ampicillin Resistance Pattern and Aerobic Bacterial Profile in Diabetic Foot Infection Patients in Bangladesh. Int J Recent Innov Med Clin Res 2022;4(4):25-33

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